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1.
Arq. bras. oftalmol ; 79(5): 330-332, Sept.-Oct. 2016. graf
Article in English | LILACS | ID: biblio-827977

ABSTRACT

ABSTRACT We present the case of a 31-year-old patient with toxic anterior segment syndrome (TASS) that developed after undergoing deep anterior lamellar keratoplasty (DALK). She had keratoconus, and despite wearing hard contact lenses for many years in the left eye, her vision had deteriorated; therefore, DALK was performed on this eye. The preoperative visual acuity (VA) was finger counting at 3 m. Routine DALK was performed using the "big-bubble" technique. The corneal entry incision was hydrated at the end of the surgery, which was terminated by air injection into the anterior chamber. On postoperative day 1, VA was at the level of hand movements, and the cornea was edematous. Topical high-dose dexamethasone and oral steroids were initiated considering the diagnosis of TASS. Subsequently, the patient's VA increased, and the corneal edema decreased. We believe that the use of re-sterilized cannulas may have been the likely cause of TASS. Although DALK can be performed without interfering with the anterior chamber, one should keep in mind that TASS may occur in response to the solution used to hydrate the incision site and the air injected into the anterior chamber.


RESUMO Apresentamos o relato de uma paciente com 31 anos de idade, que desenvolveu síndrome tóxica do segmento anterior (TASS) após o procedimento de transplante lamelar anterior profundo (DALK). Ela apresentava ceratocone e, apesar de ter usado lentes de contato rígidas por muitos anos no olho esquerdo, apresentou deterioração da visão nesse olho que foi submetido a procedimento DALK. A acuidade visual (VA) era de conta dedos a três metros. O procedimento DALK de rotina foi realizado utilizando técnica de bolha grande (Big Bubble). A incisão de entrada da córnea foi hidratada ao final da cirurgia que foi terminada com a injeção de ar na câmara anterior. No primeiro dia de pós-operatório a VA era de percepção de movimentos da mão e a córnea estava edemaciada. Dexametasona tópica em alta dose e esteróides orais foram iniciadas ao se considerar o diagnóstico de TASS. Acreditamos que o uso de cânulas reesterilizadas podem ter sido a causa provável da TASS. A VA melhorou e o edema da córnea do diminuiu durante a evolução. Embora o procedimento DALK foi realizado sem interferir com câmara anterior, deve-se ter em mente que TASS pode ocorrer com a solução utilizada para hidratar o local da incisão e o ar injetado na câmara anterior.


Subject(s)
Humans , Female , Adult , Endophthalmitis/etiology , Corneal Transplantation/adverse effects , Anterior Eye Segment/pathology , Syndrome , Dexamethasone/therapeutic use , Visual Acuity , Endophthalmitis/pathology , Endophthalmitis/drug therapy , Edema , Keratoconus/surgery , Anti-Inflammatory Agents/therapeutic use
2.
Indian J Med Microbiol ; 2012 Jul-Sept; 30(3): 359-361
Article in English | IMSEAR | ID: sea-143987

ABSTRACT

Post-operative Nocardia endophthalmitis has an aggressive course and poor visual prognosis. It often masquerades as severe post-operative uveitis or toxic anterior segment syndrome due to the absence of vitreous involvement resulting in a delay in diagnosis. The poor prognosis in Nocardia endophthalmitis is due to severe intra-ocular inflammation which may lead to phthisis. Therefore, treatment with corticosteroids after appropriate antibiotics have been initiated may improve the outcome. This is an interventional case report highlighting the typical features of Nocardia endophthalmitis, which when diagnosed early and managed medically with antibiotics and steroids, resulted in an excellent visual outcome in our patient.


Subject(s)
Adrenal Cortex Hormones/administration & dosage , Anti-Bacterial Agents/administration & dosage , Anti-Inflammatory Agents/administration & dosage , Drug Therapy, Combination/methods , Endophthalmitis/diagnosis , Endophthalmitis/drug therapy , Endophthalmitis/pathology , Eye/pathology , Female , Humans , Middle Aged , Nocardia/isolation & purification , Nocardia Infections/diagnosis , Nocardia Infections/drug therapy , Nocardia Infections/pathology , Postoperative Complications/diagnosis , Postoperative Complications/drug therapy , Postoperative Complications/pathology
3.
Indian J Ophthalmol ; 2009 Jul; 57(4): 306-308
Article in English | IMSEAR | ID: sea-135966

ABSTRACT

Endogenous fungal endophthalmitis is most commonly caused by Candida species and usually occurs in patients with chronic diseases such as diabetes mellitus and renal insufficiency. Voriconazole, a broad-spectrum triazole antifungal agent, attains therapeutically significant concentrations in the vitreous cavity after systemic administration. We report, the successful management of presumed endogenous Candida endophthalmitis in a patient with multiple diseases and unstable systemic status with oral voriconazole. Though fungal endophthalmitis has been successfully treated with a combination of intravenous and intravitreal voriconazole, to the best of our knowledge this is the first report in ophthalmic literature (Medline Search) on the treatment of fungal endophthalmitis with only the oral route of administration of voriconazole.


Subject(s)
Administration, Oral , Aged , Antifungal Agents/administration & dosage , Candidiasis/drug therapy , Endophthalmitis/metabolism , Endophthalmitis/microbiology , Endophthalmitis/pathology , Exudates and Transudates/drug effects , Exudates and Transudates/metabolism , Humans , Male , Pyrimidines/administration & dosage , Treatment Outcome , Triazoles/administration & dosage , Vitreous Body/drug effects , Vitreous Body/metabolism , Vitreous Body/pathology
4.
Med. interna (Caracas) ; 12(2): 82-7, 1996. ilus, tab
Article in Spanish | LILACS | ID: lil-230640

ABSTRACT

Nosotros describimos un paciente con lesiones espontáneas ulcerosas, en sacabocado, localizadas en la región escapular derecha, septicemia e infección por Strepcoco Pyogens. El paciente presentó los signos y síntomas siguientes: fiebre, vómito, mialgias, desorientación, complicado con derrame pericárdico purulento, derrame pleural, meningitis, endoftalmitis ojo derecho. Recuperándose después de la terapia antimicrobiana empleada inicialmente; Vancomicina-Tobramicina, vía endovenosa, posteriormente cambiada a Penicilina Cristalina al obtener los resultados de hemocultivo


Subject(s)
Humans , Male , Aged , Anti-Bacterial Agents/therapeutic use , Pericardial Effusion/classification , Endophthalmitis/pathology , Meningitis , Sepsis/diagnosis , Streptococcus pyogenes/classification , Streptococcus pyogenes/pathogenicity
5.
Rev. bras. oftalmol ; 54(10): 775-81, out. 1995. tab
Article in Portuguese | LILACS | ID: lil-280013

ABSTRACT

O trauma ocular, causa comum de cegueira unilateral, é mais frequente em crianças e adultos jovens (predominantemente do sexo masculino). Habitualmente é provocado por agressöes, acidentes domésticos e com veículos motores e constitue a quarta causa mais importante de cegueira na maioria dos países da America LAtina. Em decorrênciade trauma ocular penetrante, um microrganismo pode ter acesso ao lho, com ou sem a presença de corpo estranho intra-ocular, ou mesmo após uma perfuraçäo auto-selante (selt sealing). Neste estudo, na Fundaçäo e Instituto Hilton Rocha, em Belo Horizonte, o autor analisa 213 casos de trauma ocular, em pacientes de 1979 a 1993. O estudo confirma dados da literatura concernentes a idade, tipo de acidente, os sinais oculares mais frequentes, o manejo do trauma ocular, etc. É nessaltada a ocorrência de endoftalmite, sua profilaxia e tratamento, e os organismos infectantes mais frequentes, assim como outros aspectos importantes da literatura


Subject(s)
Humans , Bacillus cereus/pathogenicity , Blindness/complications , Blindness/pathology , Blindness/therapy , Endophthalmitis/pathology , Endophthalmitis/rehabilitation , Endophthalmitis/therapy , Eye Injuries/complications , Eye Injuries/diagnosis , Eye Injuries/rehabilitation
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